Methyl 5-bromo-4-hydroxynicotinate

Methyl 5-bromo-4-hydroxynicotinate - Names and Identifiers

Name	Methyl 5-bromo-4-hydroxynicotinate
Synonyms	Methyl 5-bromo-4-hydroxynicotinate Methyl 5-broMo-4-hydroxynicotinate 3-Pyridinecarboxylic acid, 5-bromo-1,4-dihydro-4-oxo-, methyl ester
CAS	1175512-08-9 1052114-83-6
InChI	InChI=1S/C7H6BrNO3/c1-12-7(11)4-2-9-3-5(8)6(4)10/h2-3H,1H3,(H,9,10)

Methyl 5-bromo-4-hydroxynicotinate - Physico-chemical Properties

Molecular Formula	C7H6BrNO3
Molar Mass	232.03
Density	1.737±0.06 g/cm3(Predicted)
Boling Point	309.2±42.0 °C(Predicted)
pKa	7.45±0.69(Predicted)
Storage Condition	Inert atmosphere,Room Temperature

Methyl 5-bromo-4-hydroxynicotinate - Introduction

Methyl 5-bromo-4-hydroxypyridine-3-carboxylate, also known as methyl bromopicolinate, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: 5-bromo -4-hydroxyl pyridine -3-carboxylic acid methyl ester is colorless or slightly yellow liquid.
2. molecular formula: C≡H≡BrNO₂.
3. Molecular weight: 216.03g/mol.
4. Melting point: about 9 ℃.
5. Boiling point: about 112 ℃.

Use:
1. As a reagent in organic synthesis, it is commonly used in the synthesis of other organic compounds.
2. It is often used to synthesize biologically active molecules in drug research and manufacturing.

Preparation Method:
5-Bromo-4-hydroxypyridine-3-carboxylic acid methyl ester can be prepared by the following method:
4-hydroxypyridine and methyl bromoformate are reacted under appropriate conditions to obtain the target product.

Safety Information:
1. 5-Bromo-4-hydroxypyridine-3-carboxylic acid methyl ester is an organic compound, which has certain danger. It is necessary to strictly abide by the safety operation regulations during operation.
2. avoid inhalation, contact with skin and eyes, use should wear protective gloves, protective glasses and other personal protective equipment.
3. in case of contact or misuse, rinse immediately with plenty of water and seek medical attention as soon as possible.
4. should be stored in a cool, dry, well-ventilated place, away from fire and oxidant.

Last Update：2024-04-09 02:00:41